Which of the following symptoms indicates potential lead poisoning?

The correct choice highlights fatigue and irritability as symptoms indicative of potential lead poisoning. Lead can affect the nervous system and lead to various neuropsychological symptoms. Individuals exposed to lead may experience cognitive impairments, mood changes, and emotional disturbances, which can manifest as irritability and overall fatigue.

In contrast, while other symptoms might be present in various health conditions, they are not as specific or commonly recognized as indicators of lead poisoning. Frequent colds could relate to general health issues or a weak immune system but are not directly linked to lead exposure. Weight loss can be attributed to multiple factors, including dietary changes, illness, or stress, making it a less specific indicator. Headaches can occur for numerous reasons, including tension, dehydration, or other environmental factors, but they do not specifically point to lead poisoning like fatigue and irritability do. Therefore, recognizing fatigue and irritability as signs of lead poisoning can help in early detection and intervention.